{"id":12299,"date":"2025-05-21T08:36:17","date_gmt":"2025-05-21T06:36:17","guid":{"rendered":"https:\/\/alivitpharm.djole.dog\/?page_id=12299"},"modified":"2025-05-21T11:18:37","modified_gmt":"2025-05-21T09:18:37","slug":"sweet-wormwood","status":"publish","type":"page","link":"https:\/\/alivitpharm.djole.dog\/sq\/sweet-wormwood\/","title":{"rendered":"Pelini i \u00ebmb\u00ebl"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"12299\" class=\"elementor elementor-12299\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ba433ad elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ba433ad\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5e9d3d4\" data-id=\"5e9d3d4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c9679c5 elementor-widget elementor-widget-heading\" data-id=\"c9679c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Pelini i \u00ebmb\u00ebl<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a034b5 elementor-widget elementor-widget-image\" data-id=\"3a034b5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"75\" height=\"33\" src=\"https:\/\/alivitpharm.djole.dog\/wp-content\/uploads\/2019\/07\/logo-leaf-new.png\" class=\"attachment-large size-large wp-image-2518\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ae1a0f elementor-widget elementor-widget-text-editor\" data-id=\"8ae1a0f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>Artemisia annua L. &#8211; Asteraceae<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0daa588 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0daa588\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3b7e5de\" data-id=\"3b7e5de\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-53f8eac elementor-widget elementor-widget-image\" data-id=\"53f8eac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/alivitpharm.djole.dog\/wp-content\/uploads\/2025\/05\/sweet-wormwood.jpg\" title=\"sweet-wormwood\" alt=\"Pelini i \u00ebmb\u00ebl\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b94d03a elementor-widget elementor-widget-text-editor\" data-id=\"b94d03a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Pelini i \u00ebmb\u00ebl<\/strong> \u00ebsht\u00eb nj\u00eb bim\u00eb barishtore nj\u00ebvje\u00e7are nga gjinia <em>Artemisia<\/em> q\u00eb i p\u00ebrket familjes <em>Asteraceae<\/em>. Rritet n\u00eb natyr\u00eb si bim\u00eb bar\u00ebrash. \u00cbsht\u00eb nj\u00eb varietet autokton nga rajonet e buta t\u00eb Azis\u00eb, por p\u00ebr shkak t\u00eb r\u00ebnd\u00ebsis\u00eb s\u00eb tij medicinale, \u00ebsht\u00eb i p\u00ebrhapur n\u00eb t\u00eb gjith\u00eb bot\u00ebn, ve\u00e7an\u00ebrisht n\u00eb Evrop\u00ebn Jugore dhe Juglindore dhe Amerik\u00ebn e Veriut.<\/p><p>Ekziston nj\u00eb histori e gjat\u00eb e p\u00ebrdorimit t\u00eb pjes\u00ebve ajrore dhe gjetheve t\u00eb <em>A. annua<\/em> p\u00ebr q\u00ebllime mjek\u00ebsore n\u00eb disa vende aziatike. Pjesa ajrore e pelinit t\u00eb \u00ebmb\u00ebl p\u00ebrdoret si ila\u00e7 tradicional, nd\u00ebrsa gjethet p\u00ebrdoren si l\u00ebnd\u00eb e par\u00eb p\u00ebr nxjerrjen e artemisinin\u00ebs. Pelini i \u00ebmb\u00ebl p\u00ebrdoret si nj\u00eb ila\u00e7 tradicional bimor p\u00ebr humbjen e p\u00ebrkohshme t\u00eb oreksit, p\u00ebr \u00e7rregullime t\u00eb lehta dispeptike\/gastrointestinale.<\/p><p>Aktiviteti farmakologjik kund\u00ebr s\u00ebmundjeve kronike dhe infektive t\u00eb metabolit\u00ebve t\u00eb ndrysh\u00ebm nga <em>A. annua<\/em>, artemisinina dhe derivatet e saj, flavonoidet dhe vajrat esencial\u00eb, \u00ebsht\u00eb mb\u00ebshtetur nga prova eksperimentale paraklinike si in vivo ashtu edhe in vitro, dhe \u00ebsht\u00eb arritur n\u00eb p\u00ebrfundimin nga v\u00ebzhgimet klinike te njer\u00ebzit e trajtuar me pjes\u00eb t\u00eb ndryshme t\u00eb bim\u00ebs, kryesisht gjethet, n\u00eb trajtimin e malaries. Gjethet, farat dhe e gjith\u00eb bima e <em>A. annua<\/em> kan\u00eb treguar gjithashtu aktivitet farmakologjik kund\u00ebr parazit\u00ebve p\u00ebrgjegj\u00ebs p\u00ebr leishmanioz\u00ebn dhe s\u00ebmundjen Chagas. Raporti i par\u00eb mbi efikasitetin in vivo t\u00eb <em>A. annua<\/em> kund\u00ebr etheve t\u00eb dengues \u00ebsht\u00eb botuar s\u00eb fundmi.<\/p><p>M\u00eb i njohuri nga t\u00eb gjith\u00eb p\u00ebrb\u00ebr\u00ebsit aktiv\u00eb \u00ebsht\u00eb seskuiterpeni artemisinin dhe derivatet e tij kimike. Bima jo vet\u00ebm q\u00eb \u00ebsht\u00eb e pasur me polifenole, flavonoide, proteina, kumarina, fitosterole, polisakaride, por \u00ebsht\u00eb gjithashtu e pasur me kalium, selen, nitrate dhe krip\u00ebra inorganike. Vajrat esencial\u00eb t\u00eb avulluesh\u00ebm jan\u00eb t\u00eb pranish\u00ebm n\u00eb p\u00ebrqendrime prej 0,20 \u2013 0,25%. P\u00ebrb\u00ebr\u00ebs t\u00eb tjer\u00eb t\u00eb r\u00ebnd\u00ebsish\u00ebm p\u00ebrfshijn\u00eb kamfenin, ketonin, kamforin, betakariofilenin, pinenin.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7a904f2 elementor-widget elementor-widget-image\" data-id=\"7a904f2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/alivitpharm.djole.dog\/wp-content\/uploads\/2022\/09\/leaves.png\" title=\"leaves\" alt=\"Leaves\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0379ab8 elementor-widget elementor-widget-text-editor\" data-id=\"0379ab8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Artemisinina \u00ebsht\u00eb modifikuar kimikisht nga kompanit\u00eb farmaceutike p\u00ebr t\u00eb p\u00ebrmir\u00ebsuar tretshm\u00ebrin\u00eb e saj n\u00eb uj\u00eb (artesunate) ose yndyr\u00eb (artemeter). K\u00ebto derivate jan\u00eb pretenduar t\u00eb jen\u00eb 5 her\u00eb m\u00eb efektive se artemisinina, por t\u00eb dh\u00ebnat shkencore p\u00ebr t\u00eb mb\u00ebshtetur k\u00ebt\u00eb pretendim jan\u00eb t\u00eb pakta.<\/p><p>Gjat\u00eb 40 viteve t\u00eb fundit, nj\u00eb num\u00ebr i madh punimesh t\u00eb rishikuara nga koleg\u00ebt kan\u00eb p\u00ebrqendruar k\u00ebrkimet e tyre n\u00eb aktivitetin antiparazitar t\u00eb artemisinin\u00ebs. N\u00eb ve\u00e7anti, polifenolet dhe flavonoidet tani konsiderohen si substanca ky\u00e7e n\u00eb efikasitetin e <em>A. annua<\/em> dhe bim\u00ebve t\u00eb tjera t\u00eb k\u00ebsaj familjeje. Flavonoidet si artemetina, rutina, kuercetina, kasticina, eupatina, luteolina dhe glukozidet e tyre kan\u00eb nj\u00eb gam\u00eb t\u00eb gjer\u00eb aktivitetesh biologjike, shum\u00eb prej t\u00eb cilave kan\u00eb efekte sinergjike. Luteolina ka treguar aktivitet antimalarik dhe antioksidues. P\u00ebrb\u00ebr\u00ebsit kryesor\u00eb t\u00eb vajit esencial t\u00eb <em>A. annua<\/em> jan\u00eb cineoli, kamfeni, \u03b1-pineni, germakreni, ketoni i kamforit. Ato jan\u00eb t\u00eb pranishme n\u00eb p\u00ebrqendrime prej 0,20 - 0,25% dhe kan\u00eb treguar jo vet\u00ebm aktivitete t\u00eb ndryshme antimikrobike, por edhe aktivitete anti-inflamatore dhe citotoksike. Acidet fenolike, acidet klorogjenike dhe rosmarinike jan\u00eb t\u00eb pranishme n\u00eb ekstraktin ujor t\u00eb <em>A. annua<\/em>. Ato jan\u00eb antioksidant\u00eb t\u00eb fuqish\u00ebm dhe mund t\u00eb zvog\u00eblojn\u00eb sekretimin e citokinave anti-inflamatore, interleukin-6 dhe interleukin-8.<\/p><p><em>A. annua<\/em> zakonisht quhet \"pelin\" sepse \u00ebsht\u00eb anthelmintik, dhe k\u00ebto veti t\u00eb pelinit t\u00eb \u00ebmb\u00ebl kan\u00eb qen\u00eb t\u00eb njohura q\u00eb nga koh\u00ebrat e lashta. Nj\u00eb studim vuri n\u00eb dukje se <em>A. annua<\/em> \u00ebsht\u00eb efektive n\u00eb trajtimin e shistosomiaz\u00ebs (bilharzia), e cila \u00ebsht\u00eb s\u00ebmundja e dyt\u00eb m\u00eb e r\u00ebnd\u00ebsishme n\u00eb Afrik\u00ebn tropikale. Universiteti i Cuman\u00ebs n\u00eb Venezuel\u00eb kreu nj\u00eb studim n\u00eb vitin 2013 mbi efektin e <em>A. annua<\/em> n\u00eb epimastigotet e T. cruzi. Pas nj\u00eb trajtimi 7-ditor, dend\u00ebsia e parazitit u zvog\u00eblua ndjesh\u00ebm.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aaa7eda elementor-widget elementor-widget-heading\" data-id=\"aaa7eda\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Referencat<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ccb564c elementor-widget elementor-widget-text-editor\" data-id=\"ccb564c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li style=\"list-style-type: none;\"><ul><li><a class=\"reference-link\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0926669011003219\" target=\"_blank\" rel=\"noopener\">Chemical composition and antioxidant and antimicrobial activity of essential oil of Artemisia annua L. from Bosnia<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32758647\/\" target=\"_blank\" rel=\"noopener\">Traditional application and modern pharmacological research of Artemisia annua L<\/a><\/li><\/ul><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Sweet Wormwood Artemisia annua L. &#8211; Asteraceae Sweet wormwood is an annual herbaceous plant from the genus Artemisia that belongs to the family of Asteraceae. It grows in nature as a weed plant. It is an autochthonous variety from the temperate regions of Asia, but due to its medicinal importance, it is spread all over [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-12299","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/pages\/12299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/comments?post=12299"}],"version-history":[{"count":0,"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/pages\/12299\/revisions"}],"wp:attachment":[{"href":"https:\/\/alivitpharm.djole.dog\/sq\/wp-json\/wp\/v2\/media?parent=12299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}